Oxycodone combinations for pain relief

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Oxycodone for cancer-related pain.

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Treatment with prolonged-release oxycodone/naloxone improves pain relief and opioid-induced constipation compared with prolonged-release oxycodone in patients with chronic severe pain and laxative-refractory constipation.

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Oxycodone is a valued opioid analgesic, which may be administered either as the first strong opioid or when other strong opioids are ineffective. In case of insufficient analgesia and/or intense adverse effects such as sedation, hallucinations and nausea/vomiting a switch from another opioid to oxycodone might be beneficial. Oxycodone is administered to opioid-naive patients with severe pain an...

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ژورنال

عنوان ژورنال: Drugs of Today

سال: 2010

ISSN: 1699-3993

DOI: 10.1358/dot.2010.46.6.1470106